Age-Adjusted D-Dimer Cutoff
Age-adjusted D-dimer cutoff (ADJUST-PE, JAMA 2014): 500 ug/L up to age 50 and age × 10 ug/L above age 50; below the cutoff makes VTE unlikely at a non-high pretest probability.
Open the calculator → Runs in your browser. Data leaves only if you deliberately send a problem report from the interactive tool.
Example
- Age
- 75 years
- D-dimer
- 600 ug/L FEU
Result: Age-adjusted D-dimer cutoff 750 ug/L — D-dimer 600 is below the cutoff (VTE unlikely at non-high pretest probability).
The tool opens with these values already filled in. Replace them with your own.
What the result means
- D-dimer < cutoff
- VTE unlikely at a non-high clinical pretest probability.
- D-dimer >= cutoff
- Elevated — not diagnostic. Use only with a validated pretest-probability rule. A threshold aid, not a diagnosis.
What you enter
- Age
- D-dimer
How this is calculated
Righini M, Van Es J, Den Exter PL, et al. Age-adjusted D-dimer cutoff levels to rule out pulmonary embolism: the ADJUST-PE study. JAMA. 2014;311(11):1117-1124. Read the source ↗
A reference and educational tool. Not medical, legal, or financial advice, and not a substitute for clinician judgment.